CLINICAL STUDIES AND RESEARCH REPORTS
I. Medical Research Reports on Kintopill™
Medical research reports on KINTOPILL (abstract)
Analysis of Weight-Reducing/ reduction? Effects of Kintopill™ in Obese Rats
(Chen Yu, et al. Department of Pathophysiology,
Shanghai Medical
University, Shanghai, 200032)
Objective: To investigate the weight-reducing effect of Kintopill™ and its probable mechanism in obese rats.
Method: The obese rats' body weight, Lee's index, total weight of celiac fat tissue, adipocyte size, blood glucose, blood lipid, expression of leptin in adipocyte (ABC method), level of surem leptin (RIA) were chosen as the indexes.
Results: After administration of Kintopill™ (40mg/100g B.W./d.), the rats lost their body weights to some extent. At the same time, blood cholesterol and glucose levels were lowered and adipocyte's leptin expression reduced, while serum leptin levels were elevated.
Conclusions: Kintopill™ reduces the weight of obese rats when it is administered to the rats for more than thirty days with a dosage of 40 mg/100g B. W./d.
The mechanism of its weight-reducing effect may be related to serum leptin elevation. It also lowers blood cholesterol levels. As obesity is frequently accompanied by hyperglycemia, blood glucose can be reduced to lower levels when Kintopill™ is administrated.
An
Experimental Study on the Preventing Obesity by Kintopill™ in
Rats
(Qu Xiaoyi, et al. Department of Pathophysiology, Shanghai Medical
University, Shanghai, 200032)
Objective: To investigate the effects of Kintopill™ in preventing obesity and its probable mechanism in obese rats.
Method: Twenty-six newborn SD rats were randomly grouped as prevention group (n=8), control group (n=8) and normal group (n=10). The rats in the prevention group and control group were fed with high-energy forage and those in the normal group were fed with ordinary forage. The rats in prevention group were administrated with Kintopill™ (40mg/100g B.W./d.) from 9th to 17th weeks.
Dynamic changes in body weight, celiac fat weight and adipocytes were measured. Immunnohistological analysis of leptin in celiac adipocytes (ABC method) and the measurement of serum leptin levals (RIA method) were conducted.
Results: The body weight and net weight
of celiac fat were lower, their adipocytes were smaller and
immunochemical stainings of leptin were weaker in the prevention
group than that in the control group. There was an obvious positive
relationship between the expression of leptin and celiac fat tissue
weight
(r=0.8663, P<0.05). But the changes in serum leptin levels were
not significant.
Conclusion: Kintopill™ (40mg/100g B.W./d.) can prevent obesity in rats fed with high-enegy forage. The mechanism may be related to the decrease of adipocytes leptin expression.
Day 1 to 7: Take the normal dosage of 2 Kintopills 3 times a day half-an-hour after meals.
Day 8 to 21: Take 3 Kintopills 3 times a day after meals. Drink plenty of water during this period with some squeezed lemon/lime. Increase your intake of citrus fruits like oranges and grapefruit during this week if possible.
Day 22 to 30: Revert to the normal dosage of 2 Kintopills 3 times a day after meals.
Day 31: Send us your testimonial after you have weighed yourself!
*Individual results may vary.
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Cindy Levin, New Jersey
"I felt
really depressed after the birth of my first child mostly because
my weight had ballooned to 172 lbs! My weight pre-pregnancy always
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and social events. I'm writing in to thank Kim, my best friend (who
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here in New Jersey even though I know you guys are from Singapore.
I'm 2 months on Kintopill and have lost 18 lbs - some way to go but
I've regained all my confidence, Thank You! You can use this as a
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this little story with her name gets put up on your site! Good
work, guys!